Simultaneous changes in seed size,oil content and protein content driven by selection of SWEET homologues during soybean domestication     

Shoudong Wang  Shulin Liu  Jie Wang  Kengo Yokosho  Bin Zhou  Ya-Chi Yu  Zhi Liu  Wolf B Frommer  Jian Feng Ma  Li-Qing Chen  Yuefeng Guan  Huixia Shou  Zhixi Tian 《国家科学评论(英文版)》2020,7(11):1776

Soybean accounts for more than half of the global production of oilseed and more than a quarter of the protein used globally for human food and animal feed. Soybean domestication involved parallel increases in seed size and oil content, and a concomitant decrease in protein content. However, science has not yet discovered whether these effects were due to selective pressure on a single gene or multiple genes. Here, re-sequencing data from >800 genotypes revealed a strong selection during soybean domestication on GmSWEET10a. The selection of GmSWEET10a conferred simultaneous increases in soybean-seed size and oil content as well as a reduction in the protein content. The result was validated using both near-isogenic lines carrying substitution of haplotype chromosomal segments and transgenic soybeans. Moreover, GmSWEET10b was found to be functionally redundant with its homologue GmSWEET10a and to be undergoing selection in current breeding, leading the the elite allele GmSWEET10b, a potential target for present-day soybean breeding. Both GmSWEET10a and GmSWEET10b were shown to transport sucrose and hexose, contributing to sugar allocation from seed coat to embryo, which consequently determines oil and protein contents and seed size in soybean. We conclude that past selection of optimal GmSWEET10a alleles drove the initial domestication of multiple soybean-seed traits and that targeted selection of the elite allele GmSWEET10b may further improve the yield and seed quality of modern soybean cultivars.  相似文献   

Application of Sigma Metrics for the Assessment of Quality Assurance in Clinical Biochemistry Laboratory in India: A Pilot Study     

Singh B  Goswami B  Gupta VK  Chawla R  Mallika V 《Indian journal of clinical biochemistry : IJCB》2011,26(2):131-135

Ensuring quality of laboratory services is the need of the hour in the field of health care. Keeping in mind the revolution ushered by six sigma concept in corporate world, health care sector may reap the benefits of the same. Six sigma provides a general methodology to describe performance on sigma scale. We aimed to gauge our laboratory performance by sigma metrics. Internal quality control (QC) data was analyzed retrospectively over a period of 6 months from July 2009 to December 2009. Laboratory mean, standard deviation and coefficient of variation were calculated for all the parameters. Sigma was calculated for both the levels of internal QC. Satisfactory sigma values (>6) were elicited for creatinine, triglycerides, SGOT, CPK-Total and Amylase. Blood urea performed poorly on the sigma scale with sigma <3. The findings of our exercise emphasize the need for detailed evaluation and adoption of ameliorative measures in order to effectuate six sigma standards for all the analytical processes.  相似文献   

渍害土壤肥力综合评价研究——以湖北省潜江市高场农场为例   总被引：1，自引：0，他引：1  

李方敏  周治安  艾天成  原雄人 《资源科学》2002,24(1)

利用因子分析、相关分析和模糊数学原理 ,针对渍害土壤的 1 0项肥力指标进行了土壤肥力的综合评价。根据S型或抛物线型作物效应曲线建立各项肥力指标的隶属度函数 ,计算出隶属度值 ,并按各肥力指标的公因子方差、相关系数确定其权重系数 ,从而求得各渍害类型土壤肥力综合指标值 (IFI) ,检验两种方法的IFI与其对应的水稻产量间的相关性 ,表明均达极显著水平 (r=0 75 2 1 ) ,说明综合评价结果能较好地反映出土壤的肥力。  相似文献   

Effects of short-term hormone replacement on atherogenic indices in Indian postmenopausal women     

Sarika Arora  Anju Jain  R Chitra 《Indian journal of clinical biochemistry : IJCB》2006,21(1):41-47

Indian ethnicity by itself is a strong risk factor for development of CAD in Indian postmenopausal women due to lower HDL levels as compared to Whites and women of oriental origin. We evaluated and compared the short-term effects of menopause, estrogen replacement therapy and combined estrogen and progestin replacement therapy on various atherogenic indices. 40 postmenopausal women, both surgical and natural (20 each) were selected. 10 surgical postmenopausal women were given 0.625 mg conjugated estrogens daily for 6 months and 10 natural postmenopausal women were given 0.625 mg conjugated estrogen with 2.5 mg medroxyprogesterone acetate daily. 20 women were included in the control group and given placebo. Fasting venous blood samples were analyzed for extended lipid profile and calculated atherogenic indices before starting the therapy and after 1,3 and 6 months. LDL and Apolipoprotein B increased (p<0.05) and those of Apolipoprotein A1 and HDL decreased in the control groups. In both the study groups levels of serum cholesterol and LDL decreased (p<0.05) and those of HDL and Apolipoprotein A1 increased (p<0.01). LDL/HDL, Apo B/ApoA1, Total Cholesterol/HDL decreased significantly (p<0.05) in both the study groups compared to the control groups. The effect of estrogen alone was more significant as compared to combination therapy. Log Triglycerides (TG)/HDL ratio showed a decrease in women on estrogen alone but the difference was not significant. Our study confirms that short term HRT has a favorable effect on atherogenic indices in Indian postmenopausal women.  相似文献   

An audit of total and free thyroxine measurements in screening for hypo and hyperthyroidism in patients using chemiluminescence immunoassay     

J. J. Fleming  S. Rajaratnam  M. S. Seshadri  A. S. Kanagasabapathy 《Indian journal of clinical biochemistry : IJCB》2001,16(1):95-100

An audit of 2509 patient specimens analyzed for both total thyroxine (TT4) and free thyroxine (FT4) by the ACS-180 automated chemiluminescence immunoassay analyzer revealed that there were 219 discrepancies (8.7% of the total). A discrepancy was defined as one analyte within its reference range and the other outside. The discrepant results were divided into 4 groups: group A: normal TT4, but decreased FT4, 101 patients (4.0%); group B: increased TT4, normal FT4, 78 patients (3.1%); group C: decreased TT4, normal FT4, 34 patients (1.4%); and group D: normal TT4, increased FT4, 6 patients (0.2%). TSH measurements were available, by a 3^rd generation chemiluminescent assay, in 142 of these patients, and were consistent with the FT4 result in 72 patients, with TT4 in 61 cases and with neither in 9 patients. The clinical diagnosis was investigated in a subgroup of 43 endocrine patients. Thirteen of the 20 endocrine patients in group A were diagnosed as hypothyroid, with a measured serum TSH, in 11 of them, of median 14.6, range 1.2 to 46.2 μlU/ml. Eleven of the 19 endocrine patients in group B were on thyroid replacement, with a measured serum TSH, in 7 of them of <0.01 μlU/ml. The audit of current laboratory practice led to a suggestion to replace the current thyroid function screening strategy of measuring both TT4 and FT4 by the combination of FT4 and TSH. The reasons for the discrepancies and the alternative strategies for screening of thyroid function are discussed.  相似文献   

The impact of R&D spillovers on UK manufacturing TFP: A dynamic panel approach     

Dolores Añón Higón 《Research Policy》2007,36(7):964-979

One of the benefits claimed for investment in Research and Development (R&D) is that there is a spillover effect. Industries benefit from both their own R&D efforts as well as the efforts of other national and overseas industries. The present research presents new evidence on the long-term impact of R&D investment upon UK industry's productivity performance and on the nature of these “R&D spillovers”. The results suggest that R&D efforts from the industry itself and from other national industries have a positive impact on the industry's productivity but, interestingly, there is no gain from foreign R&D investment.  相似文献   

虫霉的大量生产及其在害虫生物防治中的应用     

刘青娥 《丽水学院学报》2005,27(2):52-54,57

虫霉是一种重要的昆虫病原真菌,它们流行性强,是生物防治中开发的重要资源。虫霉的培养和生产比较困难,但近年来进展较大,少数已可工业生产。虫霉的休眠孢子、分生孢子和菌丝皆可生产,各具利弊。虫霉的利用主要包括自然流行病、淹没式放菌、接种式放菌诱导和引种定殖等方式。  相似文献   

汕优63组合的高产制种技术措施     

葛明永 《安徽科技学院学报》1996,(4)

杂交水稻制种产量较低，这是育种界多年来力求解决的问题。１９９５年，全地区汕优６３组合制种１６６．７ｍ２，平均单产２８１２．５ｋｇ·ｈｍ－２，其中单产超３０００ｋｇ·ｈｍ－２的有３４ｈｍ２。  相似文献   

广州市江村水源地的岩溶水资源研究     

刘尚仁 《中山大学学报论丛》1990,(4)

江村水源地的隐伏岩溶,是以前的岩溶地面在晚更新世地壳间歇性下沉和海侵时被泥沙覆盖形成的.该水源地属半埋藏阶地,江村水源地1974～1983年平均开采量32945m~3/d,属过量开采,它是采区静水位和降落漏斗不能复原位,呈现衰减过程的主要原因.江村水源地岩溶水长期持续的可采量为3×10~4m~3/d,开采条件下的补给模数 909m~3/d·km~2,是有供水价值的水源地。  相似文献   

磁性液体密封机理的研究   总被引：1，自引：0，他引：1  

赵四海  秦文艺 《大连大学学报》2008,29(3):115-118

根据悬浮液的分散团聚理论,提出了磁流变效应的机理,并推导出磁流变液屈服应力公式。根据磁流变流体的磁流变效应,推导出了磁性液体密封压力的计算公式,磁性液体的密封压力与磁性液体的屈服应力、密封结构的长度和间隙相关。采用狭缝式磁流变液流变性能测试系统,测试了现有磁性液体的屈服应力,对已有的磁流体密封装置进行了实验研究,该公式计算结果与实验结果吻合。  相似文献